The U.S. Department of Energy (DOE) has announced new collaboration agreements with 24 organizations to support the Genesis Mission, a national initiative focused on using artificial intelligence (AI) to advance scientific discovery, strengthen national security, and drive innovation in the energy sector. The move is part of ongoing efforts to implement President Trump’s Executive Order on Removing Barriers to American Leadership In Artificial Intelligence and follows the release of the America’s AI Action Plan earlier this year.
At a White House meeting attended by industry representatives, Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy (OSTP), participants discussed public-private partnerships aimed at developing scalable national infrastructure for AI research.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
Dr. Darío Gil stated: “Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation. These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The 24 organizations signing memorandums of understanding with DOE include major technology firms such as Accenture, AMD, Amazon Web Services, Google, IBM, Intel, Microsoft, NVIDIA, OpenAI, Oracle; as well as other companies like Anthropic and XPRIZE. These partners have either responded to a DOE request for information or are already working with DOE or its National Laboratories on projects related to the Genesis Mission.
According to DOE officials any products developed through these collaborations will be architecture-agnostic—meaning they can work across different computing platforms—and are intended to support a broad range of scientific applications.
DOE plans further meetings with private industry collaborators as well as academic institutions and philanthropic groups in order to expand participation in the Genesis Mission. The Department is also accepting submissions through open requests for information (RFIs), including one on transformational AI models that remains open until January 14th 2026; another focused on national security applications closes January 23rd 2026.
More details about the Genesis Mission are available at www.genesis.energy.gov.
