HHS seeks public input on accelerating artificial intelligence use in clinical care

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HHS seeks public input on accelerating artificial intelligence use in clinical care

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Thomas Keane, MD, MBA, Assistant Secretary for Technology Policy/National Coordinator for Health Information Technology (ASTP/ONC) | Official Website

The U.S. Department of Health and Human Services (HHS) has released a Request for Information (RFI) to gather public input on ways to increase the use of artificial intelligence (AI) in clinical care across the country.

The initiative aims to advance President Trump’s policy on maintaining American leadership in AI and aligns with Secretary Kennedy’s goal to "Make America Healthy Again." The department is seeking feedback from stakeholders on how regulatory, reimbursement, and research strategies can be used to support AI adoption in health care.

The HHS Office of the Deputy Secretary is leading this strategy. The office is asking for input on several issues, including how AI can improve patient and caregiver experiences, lower provider workload, raise quality of care, and reduce health care costs for both consumers and government.

"Artificial intelligence will be a transformative force for good across America," said HHS Deputy Secretary Jim O’Neill. "We want to hear from you. Our efforts to accelerate AI adoption must be guided by the real needs and experiences of those developing these tools and delivering care."

As technology progresses, HHS is focusing on interoperability as well as data privacy under HIPAA regulations. Dr. Thomas Keane, MD, MBA, Assistant Secretary for Technology Policy and National Coordinator for Health IT stated: "Artificial intelligence is powered by data. Data liquidity and the trust patients and providers have in how data moves are essential. Through our interoperability work, we are designing for both, bringing true data access to patients and enabling AI. We look forward to hearing how these tools can best strengthen care."

HHS also seeks comments on how digital health regulations should adapt for AI-driven technologies while ensuring patient safety; how payment systems could better support efficient technologies; and what kinds of research investments might help put new practices into use—especially in complex or serious medical cases.

In addition, the department encourages responses that consider medium- and long-term challenges facing health care, such as conditions like frailty or dementia that may become more common over time.

This announcement extends HHS's internal “OneHHS” approach—focused on using AI within its own operations—to include broader efforts aimed at speeding up AI use throughout the entire U.S. health system.

Further information about the RFI can be found at https://www.federalregister.gov/public-inspection/2025-23641/request-for-information-accelerating-the-adoption-and-use-of-artificial-intelligence-as-part-of

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